To treat HIV-infected individuals, one approach is therapeutic vaccination that aims to induce durable immunity by reactivating the individual’s immune system to HIV. Ideally, this would lead to viral control without taking combined anti-retroviral therapy (cART).
In this project, we examine several cohorts with -omics technology to try and understand the effect that these DC vaccinations have on vaccinated individuals.
Publications
DC immunotherapy in HIV-1 infection induces a major blood transcriptome shift
Anna L. de Goede, Arno C. Andeweg, Henk-Jan van den Ham, Maarten A. Bijl, Fatiha Zaaraoui-Boutahar, Wilfred F.J. van IJcken, Sofie Wilgenhof, Joeri L. Aerts, Rob A. Gruters, Albert D.M.E. Osterhaus